Prof. M.D. Mehmet YOKUŞOĞLU

1982-1989 Gulhane Military Medical Faculty (Undergraduate)
1992-1996 Gulhane Military Medical Faculty, Department of Cardiology (Specialization)
Associate Professorship: 2006
Professorship: 2013

1990-1992 Maltepe Military High School Head of Health Department
1992-1996 Gulhane Military Medical Faculty Cardiology Specialist
1996-1998 Marshal Çakmak Hospital Cardiology Service Chief Erzurum
1998-1999 Gulhane Military Medical Academy Cardiology Asst. Assoc. Ankara
1999-2003 Genk. Health Attaché Baku/Azerbaijan
2003-2006 Gulhane Military Medical Academy, Department of Cardiology. Yard. Assoc. Ankara
2006-2013 Gulhane Military Medical Academy Cardiology Department Assoc.
2013 Gülhane Military Medical Academy Cardiology Department prof.
2014-2016 Private Özkaya Medical Center
2017-2018 Private Ankara Surgical Medical Center
2018-2019 Ankara Medicana Hospital
2018-2021 Private Medisun Hospital
2019-2022 Private A Life Hospital
2022- Private Sincan Koru Hospital

Diagnosis, follow-up and medical treatment of coronary artery diseases,
Diagnosis, follow-up and treatment of systemic hypertension and pulmonary hypertension,
Diagnosis, follow-up and medical treatment of heart valve diseases,
Diagnosis, follow-up and treatment of heart failure,
Diagnosis, follow-up and medical treatment of heart rhythm disorders
Diagnosis and follow-up of congenital heart diseases

1. M. Yokuşoğlu, C. Sağ, H. Karaeren, H. Kurşaklıoğlu, S. Köse, E. Demirtaş. Assesing the cause of T wave inversion in precordial leads with ECG mapping. J Electrocardiol 1998;31:125-132.
2. O Baysan, M Yokusoglu, M Uzun, K Erinc, C Genc, A Kirilmaz, C Koz, H Karaeren, C Sag, E Isik. Left atrial functions after myocardial infarction. Heart and Vessels 2005;20:56-60
3. M Ozkan, C Sag, M Yokusoglu, M Uzun, O Baysan, K Erinc, E Isik. The effect of tirofiban and clopidogrel pretreatment on outcome of old saphenous vein graft stenting in patients with acute coronary syndromes. Tohoku J Exp Med 2005;206:7-13
4. M Yokusoglu, M Uzun, O Baysan, K Erinc, C Sag, M Ozkan, H Karaeren, C Genc, E Isık. Elongation index as a new index determining the severity of left ventricular systolic dysfunction and mitral regurgitation in patients with congestive heart failure. Echocardiography 2005;22:555-560
5. M Ozkan, M Uzun, K Erinc, C Koz, O Baysan, C Sag, E Kardesoglu, M Yokusoglu, C Genc, E Işık. Utility of myocardial performance index measured by left ventricular catheterization. Acta Cardiol. 2005;60:415-420.
6. M Ozkan, O Baysan, K Erinc, C Koz, M Yokusoglu, M Uzun, C Sag, C Genc, H Karaeren, E Isik. Brain natriuretic peptide and the severity of aortic regurgitation: Is there any correlation? J Int Med Res 2005;33:537-544
7. E Bozkanat, E Tozkoparan, O Baysan, Ö Deniz, F Çiftçi, M Yokuşoğlu. The significance of elevated brain natriuretic peptide levels in chronic obstructive pulmonary disease. J Int Med Res 2005;33: 454-459
8. M Uzun, O Baysan, K Erinc, M Ozkan, C Sag, C Genc, H Karaeren, M Yokusoglu, E Isık. A simple different method to use proximal isovelocity surface area (PISA) for measuring mitral valve area. Int J Cardiovasc Imaging 2005;21:633-40
9. MB Yilmaz, M Pinar, I Naharci, B Demirkan, O Baysan, M Yokusoglu, K Erinc, I Tandogan, E Isik. Being Well-Informed About Statin is Associated with Continuous Adherence and Reaching Targets. Cardiovasc Drugs Ther 2005;19:437-40
10. C Sag, M Yokusoglu, M Cincik, M Ozkan, H Kayir, M Uzun, B Baykal, C Ozogul, O Baysan I. T Uzbay. The Prevention of Myocardial Ultrastructural Changes by Perindopril, Atenolol and Amlodipine in Chronic Alcohol Administered Rats. Pharmacol Res 2006;53;142-148
11. SY Sanisoglu, C Oktenli, A Hasimi, M Yokusoglu, M Ugurlu. Prevalence of metabolic syndrome related disorders in a large adult population in Turkey. BMJ Public Health 2006;6:92
12. N Kucukarslan, A Kirilmaz, E Ulusoy, M Yokusoglu, N Gramatnikovski, E Ozal, H Tatar. Tricuspid insufficiency does not increase early after permanent implantation of pacemaker leads. J Card Surg. 2006;21: 391-4.
13. BS Oz, H Iyem, HT Akay, C Bolcal, M Yokusoglu, E Kuralay, U Demirkilic, H Tatar. Mid-term angiographic comparison of sequential and individual anastomosis techniques for diagonal artery. J Card Surg. 2006;21:471-4.
14. BS Oz, H Iyem, HT Akay, C Bolcal, M Yokusoglu, E Kuralay, U Demırkılıc, H Tatar. Risk Factors for Short and Long Term Survival in Patients Undergoing Re-Replacement Due To Prosthetic Valve Dysfunction. Heart and Vessels. 2006;21: 339-343
15. O Baysan, E Bolu, M Uzun, F Kilicarslan, K Erinc, M Pinar, A Hasimi, M Yokusoglu, C Genc, P Yelamanchili, H Karaeren, E Isik. Left Ventricular Function in Male Patients with Secondary Hypogonadism. Echocardiography 2007;24:222-7.
16. BS Oz, I Mataracı, H Iyem, E Kuralay, S Dogancı, U Demirkılıç, M Yokuşoğlu, H Tatar. Comparison of ultrasonically activated scalpel and traditional technique in radial artery harvesting: clinical research. Thorac Cardivasc Surgeon 2007;55:104-7
17. M Yokusoglu, S Ozturk, M Uzun, O Baysan, S Demirkol, Z Caliskaner, R Dundaroz, C Sag, M Karaayvaz, E Isik. The Heart Rate Variability in Patients with Allergic Rhinitis. Mil Med. 2007;172:89-101
18. C Sağ, M Uzun, C Bolcal, M Yokusoglu, C Koz, O Baysan, M Ozkan, H Karaeren, C Genc, E Isık. A New Echocardiographic Index for Assessing Left Ventricular Function and Mechanism of Mitral Regurgitation and Its Relation to Other Echocardiographic Indices. Echocardiography 2007;24:561-6
19. M Uzun, O Baysan, C Genc, M Yokusoglu, H Karaeren, E Isık. A nomogram for measurement of mitral valve area by proximal isovelocity surface area method. Echocardiography 2007;24:783-8.
20. O Nevruz, M Yokusoglu, M Uzun, S Demirkol, F Avcu, O Baysan, C Koz, T Cetin, C Sag, AU Ural, E Isik. Cardiac autonomic functions are altered in patients with acute leukemia, assessed by heart rate variabity. Tohoku J Exp Med 2007;211:121-6.
21. C Koz, M Uzun, M Yokusoglu, O Baysan, K Erinc, C Sag, A Hasimi, E Isik. Evaluation of plasma adiponectin levels in young men with coronary artery disease. Acta Cardiologica 2007;62:239-43
22. M Yokusoglu, O Nevruz, O Baysan, M Uzun, S Demirkol, F Avcu, C Koz, T Çetin, A Hasimi, AU Ural, E Isık. The altered autonomic nervous system activity in iron deficiency anemia Tohoku J Exp Med 2007; 212:397-402
23. S Uzun, H Vural, M Uzun, M Yokusoglu. State- and trait-anxiety levels before coronary angiography. J Clin Nurs. 2008;17:602-607.
24. C Koz, M Uzun, M Yokusoglu, ÜH Ulas, O Baysan, C Genc, M Cansel, E Isik. Echocardographic, electrocardiographic and clinical correlates of recurrent transient ischemic attacks; a follow-up study. South Med J 2008;101:246-51
25. M Yokusoglu, C Sag, M Cincik, M Uzun, H Kayir, C Koz, B Baykal, M Ozkan, C Ozogul, O Baysan, IT Uzbay. Perindopril, atenolol and amlodipine prevent aortic ultrastructural changes in rats exposed to ethanol. Med Sci Monitor 2008;14:BR96-102
26. C Koz, O Baysan, A Hasimi, M Cihan, M Uzun, M Yokusoglu, C Sag, E Isik. Conventional and non-conventional coronary risk factors in male premature coronary artery disease patients already having a low framingham risk score. Acta Cardiologica 2008;63:623-8
27. M Yokuşoğlu, M Eryılmaz, O Baysan. Hukuk ve etik açısından kardiyopulmoner resüsitasyon. Anadolu Kardiyol Derg 2008;8:374-8
28. Kotseva K, Wood D, Backer GD, Bacquer DD Pyorala K, Keil U, on behalf of the EUROASPIRE Study Group. EUROASPIRE III: a survey on the lifestyle, risk factors and use of cardioprotective drug therapies in coronary patients from 22 European countries. Eur J Cardiovasc Prev Rehabil. 2009;16:121-37
29. I Yavuz, H F Asgun, C Bolcal, H Bingol, M Yokusoglu, O Baysan, T Ozgurtas, U Demirkilic, H Tatar. Importance of urinary measurement of the glutathion S-transferase in renal dysfunction patients underwent on- and off-pump coronary artery bypass surgery. Thorac and Cardiovasc Surg 2009;57:125-9
30. C Koz, H Celebi, M Yokusoglu, O Baysan, A Hasimi, M Serdaroglu, M Uzun, E Isık. The relation between coronary lesion distribution and risk factors in young adults. Anadolu Kardiyol Derg 2009;9:91-5
31. S Uzun, B Kara, M Yokuşoğlu, F Arslan, MB Yılmaz, H Karaeren. The assessment adherence of hypertensive individuals to treatment and lifestyle change recommendations. Anadolu Kardiyol Derg 2009;9:102-9
32. H Karaeren, M Yokuşoğlu, Ş Uzun, O Baysan, C Köz, B Kara, A Kırılmaz, İ Naharcı, M Pınar, MB Yılmaz, M Uzun. The effect of the content of the knowledge on adherence to medication in hypertensive patients. Anadolu Kardiyol Derg 2009;9:183-8
33. C Koz, O Baysan, M Yokusoglu, M Uzun, M Yildirim, A Hasimi, BS Oz, K Erinc, H Karaeren, H Celebi, E Isik. The effects of perindopril on aortic elastic properties and inflammatory markers in hypertensive patients. Med Sci Monitor 2009;15:PI41-5
34. M Yokusoglu, M Dede, M Uzun, O Baysan, C Köz, MC Yenen, I Baser. Cardiac autonomic balance is impaired in preeclampsia. Türkiye Klinikleri J Med Sci 2009;29:605-10
35. A Güler, MA Şahin, K Karabacak, N Küçükaslan, M Yokuşoğlu, H Tatar. Alt ekstremite gecikmiş tromboembolik arteriyel tıkanmalarında aynı seansta embolektomi ve kapalı fasiyotomi beraberliği. Anadolu Kardiyol Deg 2009;9:407-10
36. E Taşcılar, M Yokuşoğlu, R Dundaroz, O Baysan, S Oztürk, Y Yozgat, A Kılıç. Cardiac autonomic imbalance in children with allergic rhinitis. Tohoku J Exp Med 2009;219:187-91
37. RE Ulusoy, MH Terekeci, O Baysan, M Yokuşoğlu, Z Işılak, Ç Öktenli. Orlistat plus low caloric diet improves cardiovascular risk factors and cardiac functions assessed by tissue Doppler echocardiograhy in obese women. T Klinikleri Tıp Bilimleri 2009;29:1155-60
38. RE Ulusoy, Ö Karabudak, M Yokusoglu, F Kılıçarslan, A Kırılmaz, BS Cebeci. Noninvazive assessment of impaired endothelial function in psoriasis. Rhematol Int. 2010;30:479-83.
39. O Baysan, M Akyol, B Bugan, M Yokusoglu, Y Gokoglan, C Genc. Speckle tracking based myocardial velocities: Our experience with a novel software. Anadolu Kardiyol Derg 2010;10:233-8
40. De Bacquer D, Dallongeville J, Heidrich J, Kotseva K, Reiner Z, Gaita D, Prugger C, Wellmann J, Wood D, De Backer G, Keil U; EUROASPIRE III Study Group. Management of overweight and obese patients with coronary heart disease across Europe. Eur J Cardiovasc Prev Rehabil. 2010;17:447-54.
41. Dallongevillle J, De Bacquer D, Heidrich J, De Backer G, Prugger C, Kotseva K, Montaye M, Amouyel P; EUROASPIRE Study Group. Gender differences in the implementation of cardiovascular prevention measures after an acute coronary event. Heart. 2010;96:1744-9.
42. H Karaeren, M Yokusoglu, HF Töre, H Kurşaklıoğlu, N Barındık, D Demirkan. Selection of aliasing velocity for proximal flow convergence region method in assessment of mitral valve area in cases with mitral stenosis. Balkan Military Medical Review. 1998;1:28-32
43. MR Dündaröz, M Denli, M Uzun, Hİ Aydın, SÜ Sarıcı, M Yokuşoğlu, S Ülgen. Analysis of heart rate variability in children with primary nocturnal enuresis. Int Urol Nephrol 2001;32:393-397
44. Tokgözoğlu L, Kaya EB, Erol C, Ergene O, EUROASPIRE III Turkey Study Group. EUROASPIRE III: Türkiye ile Avrupa’nın karşılaştırılması. Turk Kardiyol Dern Ars. 2010;38: 164-72.
45. Prugger C, Keil U, Wellmann J, de Bacquer D, de Backer G, Ambrosio GB, Reiner Z, Gaita D, Wood D, Kotseva K, Heidrich J; for the EUROASPIRE III Study Group. Blood pressure control and knowledge of target blood pressure in coronary patients across Europe: results from the EUROASPIRE III survey. J Hypertens. 2011;29:1641-1648.
46. Taşçılar ME, Yokuşoğlu M, Boyraz M, Baysan O, Köz C, Dündaröz R. Cardiac autonomic functions in obese children. J Clin Res Pediatr Endocrinol. 2011;3:60-4.
47. Kilic A, Gulgun M, Tascilar ME, Sari E, Yokusoglu M. Cardiac autonomic regulation is disturbed in children with euthyroid Hashimoto thyroiditis. Tohoku J Exp Med. 2012;226:191-5.
48. Kozan O; RiskMan Study Group. An observational study to evaluate the clinical practice of cardiovascular risk management among hypertensive patients in Turkey. Turk Kardiyol Dern Ars. 2011;39:445-55.
49. RE Ulusoy, M Yokusoglu, O Baysan, A Kirilmaz, F Kilicaslan, BS Cebeci. Ventricular functions, aortic elastic properties and endothelial functions in patients with hypertensive response to treadmill exercise test. Turk J Med Sci 2011;41:781-7
50. A Guler, MA Sahin, O Yucel, M Yokusoglu, M Gamsızkan, E Ozal, U Demirkilic, M Arslan. Proanthocyanidin prevents myocardial ischemic injury in adult rats. Med Sci Monit 2011;17:BR326-331
51. A Kılıç, M Gülgün, ME Taşçılar, E Sarı, M Yokuşoğlu. Cardiac autonomic regulation is disturbed in children with euthyroid Hashimoto thyroiditis. Tohoku J Exp Med 2012 ;226:191-5.
52. Cinar O, Cevik E, Acar A, Kaya C, Ardic S, Comert B, Yokusoglu M, Bilgi C, Meisner M, Madsen T. Evaluation of mid-regional pro-atrial natriuretic peptide, procalcitonin, and mid-regional pro-adrenomedullin for the diagnosis and risk stratification of dyspneic ED patients Am J Emerg Med 2012;30:1915-20.
53. Demirkol S, Balta S, Unlu M, Yuksel UC, Celik T, Arslan Z, Kucuk U, Yokusoglu M. Evaluation of the mean platelet volume in patients with cardiac syndrome X. Clinics (Sao Paulo). 2012;67:1019-22.
54. Demirkol S, Kucuk U, Baysan O, Balta S, Celik T, Kurt IH, Kucuk HO, Yuksel UC, Unlu M, Yokusoglu M. The impact of mitral stenosis on left atrial function assessed by two-dimensional speckle tracking echocardiography. Echocardiography 2012;29:1064-70
55. Celik T, Yuksel UC, Fici F, Celik M, Yaman H, Kilic S, Iyisoy A, Dell'oro R, Grassi G,Yokusoglu M, Mancia G. Vascular inflammation and aortic stiffness relate to early left ventricular diastolic dysfunction in prehypertension. Blood Press. 2013;22:94-100
56. Demirkol S, Balta S, Unlu M, Arslan Z, Cakar M, Kucuk U, Celik T, Arslan E, Turker T, Iyisoy A, Yokusoglu M. Neutrophils/lymphocytes ratio in patients with cardiac syndrome X and its association with carotid intima-media thickness Clin Appl Thromb Hemost 2014;20:250-5.
57. Balta S, Demirkol S, Celik T, Kucuk U, Unlu M, Arslan Z, Balta I, Iyisoy A, Kocak N, Haqmal H, Yokusoglu M. Association between coronary artery ectasia and neutrophil-lymphocyte ratio. Angiology. 2013;64:627-32.
58. Gheorghiade M, Böhm M, Greene SJ, Fonarow GC, Lewis EF, Zannad F, Solomon SD, Baschiera F, Botha J, Hua TA, Gimpelewicz CR, Jaumont X, Lesogor A, Maggioni AP; ASTRONAUT Investigators and Coordinators. Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial. JAMA. 2013 Mar 20;309:1125-35
59. McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau J, Shi VC, Solomon SD, Swedberg K, Zile MR; PARADIGM-HF Committees and Investigators. Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF). Eur J Heart Fail. 2013;15:1062-73.
60. Demirkol S, Balta S, Celik T, Arslan Z, Unlu M, Cakar M, Kucuk U, Demirbas S, Iyisoy A, Yokusoglu M. Assessment of the relationship between red cell distribution width and cardiac syndrome X. Kardiol Pol. 2013;71:480-4.
61. Fici F, Celik T, Balta S, Iyisoy A, Unlu M, Demitkol S, Yaman H, Brambilla G, Kardesoglu E, Kilic S, Yokusoglu M, Grassi G. Comparative effects of nebivolol and metoprolol on red cell distribution width and neutrophil/lymphocyte ratio in patients with newly diagnosed essential hypertension. J Cardiovasc Pharmacol. 2013;62:388-93.
62. Maggioni AP, Greene SJ, Fonarow GC, Böhm M, Zannad F, Solomon SD, Lewis EF, Baschiera F, Hua TA, Gimpelewicz CR, Lesogor A, Gheorghiade M; ASTRONAUT Investigators and Coordinators. Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial. Eur Heart J. 2013;34:3117-27.
63. Prugger C, Wellmann J, Heidrich J, De Bacquer D, Perier MC, Empana JP, Reiner Ž, Fras Z, Jennings C, Kotseva K, Wood D, Keil U; EUROASPIRE Study Group. Passive smoking and smoking cessation among patients with coronary heart disease across Europe: results from the EUROASPIRE III survey. Eur Heart J. 2014;35:590-8.
64. Demirkol S, Balta S, Kucuk U, Celik T, Arslan Z, Olgun Kucuk H, Unlu M, Cagdas Yuksel U, Samedli S, Yokusoglu M, Iyisoy A, Kursaklioglu H. Association between microvascular angina and erectile dsyfunction. Int J Impot Res. 2014;26:124-7.
65. Yılmaz S, Yokuşoğlu M, Çınar M, Şimşek İ, Baysan O, Öz BS, Erdem H, Pay S, Dinç A.  Autonomic functions in acrocyanosis assessed by heart rate variability. Eur J Rheumatol. 2014;1:18-20
66. McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile MR; PARADIGM-HF Investigators and Committees. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371:993-1004.
67. Packer M, McMurray JJ, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, Rouleau JL, Shi VC, Solomon SD, Swedberg K, Zile M, Andersen K, Arango JL, Arnold JM, Bělohlávek J, Böhm M, Boytsov S, Burgess LJ, Cabrera W, Calvo C, Chen CH, Dukat A, Duarte YC, Erglis A, Fu M, Gomez E, Gonzàlez-Medina A, Hagège AA, Huang J, Katova T, Kiatchoosakun S, Kim KS, Kozan Ö, Llamas EB, Martinez F, Merkely B, Mendoza I, Mosterd A, Negrusz-Kawecka M, Peuhkurinen K, Ramires FJ, Refsgaard J, Rosenthal A, Senni M, Sibulo AS Jr, Silva-Cardoso J, Squire IB, Starling RC, Teerlink JR, Vanhaecke J, Vinereanu D, Wong RC; PARADIGM-HF Investigators and Coordinators. Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation. 2015;131:54-61.
68. Gyberg V, De Bacquer D, Kotseva K, De Backer G, Schnell O, Sundvall J, Tuomilehto J, Wood D, Rydén L; EUROASPIRE IV Investigators. Screening for dysglycaemia in patients with coronary artery disease as reflected by fasting glucose, oral glucose tolerance test, and HbA1c: a report from EUROASPIRE IV--a survey from the European Society of Cardiology. Eur Heart J. 2015 May 14;36(19):1171-7. 
69. Saglam M, Arikan H, Vardar-Yagli N, Calik-Kutukcu E, Inal-Ince D, Savci S, Akdogan A, Yokusoglu M, Kaya EB, Tokgozoglu L. Inspiratory muscle training in pulmonary arterial hypertension. J Cardiopulm Rehabil Prev. 2015;35:198-206.
70. Gyberg V, De Bacquer D, De Backer G, Jennings C, Kotseva K, Mellbin L, Schnell O, Tuomilehto J, Wood D, Rydén L, Amouyel P, Bruthans J, Conde AC, Cifkova R, Deckers JW, De Sutter J, Dilic M, Dolzhenko M, Erglis A, Fras Z, Gaita D, Gotcheva N, Goudevenos J, Heuschmann P, Laucevicius A, Lehto S, Lovic D, Miličić D, Moore D, Nicolaides E, Oganov R, Pająk A, Pogosova N, Reiner Z, Stagmo M, Störk S, Tokgözoğlu L, Vulic D; EUROASPIRE Investigators. Patients with coronary artery disease and diabetes need improved management: a report from the EUROASPIRE IV survey: a registry from the EuroObservational Research Programme of the European Society of Cardiology. Cardiovasc Diabetol. 2015 Oct 1;14:133.
71. Küçükoğlu MS, Hanta İ, Akdeniz B, Güllülü S, Atahan E, Sayın T, Okumuş G, Önen ZP, Yokuşoğlu M, Baygül A. Clinical efficacy, safety, tolerability, and survival outcome of long-term inhaled iloprost treatment in the management of pulmonary arterial hypertension: Data from prospective multicenter observational OPTION study. Anatol J Cardiol. 2021t;25:721-732.
72. MA Şahin, M Yokusoglu, E Kuralay, E Ozal. Can right ventricular branch bypass alleviate right ventricular dysfunction? Texas Heart Institute Journal. (In press)

Turkish Cardiology Subject
European Society of Cardiology
Balkan Military Medicine Congresses
Presentation at many congresses organized by the Emergency Medicine Association
Speaker at symposiums
Panelist and session chair